We don't have a good way to achieve certain effects that are rightly gaining in popularity among web developers. (There are also some outstanding issues that need to be resolved one way or another - #544, #545, #547 and #1211, which is related to #547, spring readily to mind.) Svelte's transition system is powerful, but only applies to a fairly narrow range of problems. I just want to get this stuff out of my head and into a place where the missing pieces will hopefully be a bit clearer. If EPR works, it’ll be a game-changer.Fair warning: this will be a long rambly issue. In emergency medicine we’re always trying to blur the line between life and certain death, to create something that looks like hope where none previously existed. “The cardiothoracic surgeons have been doing something very similar for decades but this is about moving that technique forward, into the emergency department or perhaps maybe even out into the field. It can take a situation in which there are mere seconds to save someone’s life and smear that out into many minutes. Kevin Fong, a consultant anaesthetist at University College London hospital, and the author of Extremes: Life, Death and the Limits of the Human Body, said: “Emergency preservation and resuscitation is an attempt to protect a dying patient by dramatically dropping their body temperature and forcing their physiology into slow motion. The US space agency is instead investigating ways of putting astronauts into a torpor, so reducing their metabolism for extended periods. Nasa considers that full-on hibernation for interstellar travel is still a distant prospect. “We’re trying to buy ourselves more time to save lives.” “I want to make clear that we’re not trying to send people off to Saturn,” he told New Scientist. Though Tisherman’s talk was entitled Suspended Animation, he said he was not exploring ways to preserve astronauts on deep space missions. One complication of the procedure is that patients’ cells can become damaged as they are warmed up after surgery. Once we can prove it works here, we can expand the utility of this technique to help patients survive that otherwise would not.” “Now we are doing it and we are learning a lot as we move forward with the trial. “We felt it was time to take it to our patients,” Tisherman told New Scientist, which was the first to report on the work. Previous studies have shown that EPR can help save injured pigs, though it is by no means successful all the time. The trial is due to run until the end of the year, and full results are not expected until late 2020. The trial will compare the outcomes of 20 men and women who receive standard emergency care or EPR. When the heart stops and blood stops circulating, the brain quickly becomes starved of oxygen, suffering irreparable damage within about five minutes. One aim of the US trial is to reduce the brain damage that patients are often left with if they survive such serious injuries. Once the patient’s injuries have been attended to, they are warmed up and resuscitated. Rapid cooling of trauma victims is designed to reduce brain activity to a near standstill and to slow the patient’s physiology enough to give surgeons precious extra minutes, perhaps more than an hour, to operate. The first time the team performed the process was “a little surreal”, he told New Scientist magazine. ![]() He said at least one patient had had the procedure but did not elaborate on whether that patient or any others had survived. Samuel Tisherman, at the University of Maryland, in Baltimore, described the trial at a recent symposium held by the New York Academy of Sciences. The patients, who are often victims of stabbings or shootings, would normally have less than a 5% chance of survival. Known formally as emergency preservation and resuscitation, or EPR, the procedure is being trialled on people who sustain such catastrophic injuries that they are in danger of bleeding to death and who suffer a heart attack shortly before they can be treated.
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